Organic Chemistry and Biological Systems - Biochemistry

1. From molecules to living systems: complexity is obtained from simple building blocks 2. Amino acids and proteins 2.1. Proteogenic Amino Acids 2.2. Non Proteinogenic Amino Acids 2.3. Amino Acid Polymers: Proteins. Their Structure and Function 2.3.1. Proteins Folding and Structure 2.3.2. Proteins Function and Regulation 3. Nucleotides and nucleic acids: information, energy transport, catalysis 3.1. Chemical Structures of Nucleotides 3.2. Nucleotide Polymers: RNA and DNA 3.2.1. The Flow of Genetic Information 3.2.2. DNA: Storage and Transmission of Information 3.2.3. RNA: Expression of Information and Catalysis 3.3. Nucleotides Derivatives and Coenzymes 4. Sugars: energy, structures, modulation of proteins properties 4.1. Monosaccharides and Polysaccharides 4.2. Structural Support and Intracellular Storage of Fuel for Cell Metabolism 4.3. Effects of Glycans on Glycoproteins Properties 4.2.3. Sugars as Sources of Energy and Metabolic Intermediates 5. Lipids: energy, membranes, protein targeting and signal transduction 5.1. Structures of Lipids Common in Biochemistry 5.2. Lipids in Cell Metabolism 5.3. Lipids as the Constituents of Cell Membranes 5.4. Lipid Tails Target Proteins to Membranes Glossary Bibliography Biographical Sketch